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Generic Mysoline (Primidone)
Mysoline is used alone or co-administered with other drugs as an anti-seizure medication to treat epilepsy.
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Common use

Mysoline is barbiturate which is used as anticonvulsant to treat epilepsy, grand mal, psychomotor, and focal epileptic seizures. It contains primidone as an active ingredient, which turns into to phenobarbital and phenylethylmalonamide (PEMA) during its metabolism.

Dosage and direction

This medicine is taken two or four times a day. Follow all recommendations of your doctor, do not change they dose and do not interrupt treatment without his permission. Do not exceed the recommended dose.


Avoid alcohol and other depressants of central nervous system while using Mysoline as dizziness and drowsiness it causes may increase. Do not suddenly stop treatment with this medication without permission of your doctor as it may result in status epilepticus. This medications may cause suicidal thoughts. Let your doctor know if you experience anxiety, depression, mood or behavior changes, or if you feel hyperactive (mentally or physically), agitated, hostile, restless. Inform your doctor if you are breastfeeding, pregnant, plan to become pregnant, or will deliver soon while on Mysoline. This medication may cause excessive bleeding on delivery. Consult your doctor about such your conditions as l lung disease, iver disease, kidney disease.


Mysoline cannot be used in the patients with porphyria, or allergy to primidone or phenobarbital (Luminal, Solfoton).

Possible side effect

Besides sings of allergic reaction such as rash, itching, facial swelling, trouble breathing, dizziness Mysoline may cause stomach upset, clumsiness, loss of appetite, or fatigue. If the side effects mentioned above become worse or bothersome, notify. In case of double vision, sore throat, skin, seizures, fever, rash.

Drug interaction

Inform your doctor about all prescribed and over-the-counter medications and herbal products you are taking and especially about other seizure medications, griseofulvin, disulfiram, steroids, warfarin, digoxin, medication for depression, doxycycline, cyclosporine, narcotic pain medicines (codeine), muscle relaxants, certain antihistamines (diphenhydramine), alcoholic beverages.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your usually dose next day in the same regularly time.


Symptoms of overdose are not known. If you suppose that took too much of this medicine contact your doctor.


Store in a dry tight container away from sunlight at room temperature between 15-30 C (59-86 F) away from children and pets.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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