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Generic Skelaxin (Metaxalone)
Metaxalone is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) in the brain. Metaxalone is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury.
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Monthly newsletter. If you have diabetes don't make Skelqxin changes Skelasin your medicine or diet unless you Skelaxi checked with your doctor. So, you sprained your lower back shooting hoops, a stressful work week spurred on a series of tension headaches, arthritis has you waking up with stiffness and neck pain. Not valid at any other pharmacy. Enhanced Content - Document Tools. Wrote suicide note Skelaxxin wall in ketchup. Need the lowest prices on several drugs? Skeletal muscle relaxants M Soccer player with a Hx of knee injuries and on pain meds. The duration of action of this drug is 4—6 h with a plasma half-life of 2—3 h 1 and a terminal half-life of 9 h 6. Decedent filled metaxalone prescription one day before death; 78 out of 90 pills missing. Although the activity of these metabolites is not known, metaxalone and its metabolites are not involved in significant drug—drug interactions, other than the enhancement of CNS depression. No obvious signs of alcohol or substance abuse. A simplified procedure for the isolation, characterization and identification of weak acid and neutral drugs from whole blood. Tolerance, which will be addressed as part of the final case study below, is another factor that must be considered when interpreting postmortem concentrations. Your doctor will tell you how much medicine to use.

Skelaxin - apologise, but

Major for fibromyalgia. It is important to keep all Skelaxin out of sight and reach of children as many containers such as weekly pill minders and those for eye drops, creams, patches, and inhalers are not child-resistant and young children can open them easily. Acetaminophen Dextromethorphan 1. Avoid drinking alcohol. Pediatric metaxalone ingestions reported to Texas poison control centers, — Found by friends. Use our drug basket to get the best value. Acetaminophen 14 Citalopram 0. Found by stepmother unresponsive. Take Skelaxin exactly as it was prescribed for you. All rights reserved. Not at all hard to take. Department of Agriculture. Before taking metaxalone, tell your doctor and pharmacist if you are allergic to metaxalone, any other medications, or any of the ingredients in metaxalone tablets. Sahu et al. No signs of trauma. Oil and Gas Leasing 26 documents in the last year. Although the activity of these metabolites is not known, metaxalone and its metabolites are not involved in significant drug—drug interactions, other than the enhancement of CNS depression. What side effects can this medication Skkelaxin Last seen snoring loudly. Hx of Skelaxi suicide attempt using prescription drugs. Not to be confused with Metolazonea diuretic. Your doctor may monitor your liver function and your infection-fighting white blood cells while you are taking metaxalone. Health Care Reform documents in the last year. IUPAC name 5-[ 3,5-dimethylphenoxy methyl]-1,3-oxazolidinone. Similarly, matrix effects are highly unlikely with GC-FID as a quantitative method but again are monitored on a case-by-case basis looking at pre- and post-dilution values. Skelaxin Images. IUPAC name. Tell any doctor who treats you that you are using this medicine. Because of potential for side effects, this drug is considered high risk in the elderly. In rare cases, some people may have a severe, life-threatening allergic reaction. Skelaxin is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury. Developed diarrhea, became lethargic, experienced decreased mental status immediately prior to death. It has been recognized in the literature that metaxalone is more effective in combination with analgesics 1however, at high enough concentrations the dangers of combining different types of narcotic and CNS depressant medications must also be considered. However, this medicine does not take the place of rest, exercise, physical therapy, or other treatments that your doctor may recommend for your condition. Don't have an invite code? More importantly, there were 9 cases total 7 suicides, 2 accidents where metaxalone was classified as primary with a mean of Sandra C. Decedent was supposed to be deployed overseas and was having problems at home. Found on bathroom floor a few hours later. Document Details Information about this document as published in the Federal Register. This repetition of headings to form internal navigation links has no substantive legal effect. Acetaminophen 25 Citalopram 0. Explore now. Found unresponsive in bed. The current procedure in the laboratory uses reference calibrators containing 14 acidic and neutral compounds; the procedure utilizes gas chromatography—mass spectrometry GC—MSwhich has the ability to detect additional compounds. Due to the discontinuation by Sigma-Aldrich as a supplier of p -methylphenobarbital, the laboratory replaced the internal standard with mephobarbital Grace-Davidson Discovery Sciences, Columbia, MD in late Skelaxin dosage information in more detail. Skip the missed dose if it is almost time for your next scheduled dose. Especially tell your doctor if you:. The information contained herein is not intended to cover all Skelaxin uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. It is not known whether this medicine will harm an unborn baby. Skelaxin Images. Oxford University Press is a department of the University of Oxford. By using this site, you agree to the Terms of Use and Privacy Policy. Hx of multiple medical conditions. A: The main side effect from this medication is weight loss. Hx of prior suicide attempt using prescription drugs. Skip to Content. Monthly newsletter. Prior tometaxalone was quantitated from a five-point linear regression of the calibrator responses based on the peak area ratio peak area of the metaxalone to that of the internal standard in a previously published method 3. Skelaxin metaxalone is a muscle relaxant. Discrepant results are repeated and if not consistent the case is reported as specimen unsuitable.

Skelaxin - something is

Drug Class. Especially tell your doctor if Skelaxinn take medications for:. Also tell your doctor if you have anemia or if other Skelaxih have Skelacin you to have anemia. Skelaxin Overdose Back to Top. Decedent had back surgery approx. You should bring this list with you each time you visit a doctor or if you Skelaxin admitted to a hospital. This case involved a year-old male with a history Skdlaxin post-traumatic stress disorder PTSD who was found naked on the couch by his girlfriend. Metaxalone is a generic drug also sold under the brand name Skelaxin. Metaxalone may contain different inactive ingredients than Skelaxin, talk to your doctor about the differences and choose which is best for you. It is used by patients in pain or discomfort due to muscle strain or sprain. Mayo Clinic does not endorse companies or products. You may need a dose adjustment or special tests to safely take Skelaxin. You should tell your doctor if you are breastfeeding or plan to breastfeed. Call your doctor for medical advice about side effects. Published by Oxford University Press. Ask your pharmacist any questions you have about refilling your prescription. The Skelaxin brand is manufactured by Pfizer. Ask your pharmacist for a list of the ingredients. I wanted something different.
Common use

Skelaxin is indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Metaxalone does not directly relax tense skeletal muscles in man.

Dosage and direction

The recommended dose for adults and children over 12 years of age is one 800 mg tablet three to four times a day.


It is not known whether this drug is secreted in human milk. As a general rule, nursing should not be undertaken while a patient is on a drug since many drugs are excreted in human milk.

Safety and effectiveness in children 12 years of age and below have not been established

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.


You should not use this medication if you are allergic to metaxalone, or if you have:

-anemia (a lack of red blood cells);

-severe kidney disease; or

-severe liver disease.

Side effects

Drowsiness, dizziness, headache, and nervousness or irritability;nausea, vomiting, gastrointestinal upset.hypersensitivity reaction, rash with or without pruritus;leukopenia; hemolytic anemia;jaundice.

Drug interaction

The sedative effects of Skelaxin and other CNS depressants (e.g., alcohol, benzodiazepines, opioids, tricyclic antidepressants) may be additive. Therefore, caution should be exercised with patients who take more than one of these CNS depressants simultaneously

Skelaxin may enhance the effects of alcohol and other CNS depressants.

Missed dose

If you miss a dose, take it as soon as you remember within 1 hour. Otherwise, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.


Deaths by deliberate or accidental overdose have occurred with metaxalone, particularly in combination with antidepressants, and have been reported with this class of drug in combination with alcohol.

If overdose is suspected, contact your local poison control center or emergency room immediately


Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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